A review analyzing what is COVID-19, its causes, pathogenesis, pathophysiology, and treatment


  • Mohamed Hoosen Suleman Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban 4013, South Africa


COVID-19, Pathogenesis, Pathophysiology, Treatment


The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is believed to be the causative agent for the 2019 novel coronavirus (COVID-19). The COVID-19 disease which also started from bats had mutated and it is believed to have infected pangolins as its intermediate host. Mutations of the viral pathogen thereafter led to it infecting humans. COVID-19 is considered a zoonotic disease i.e. diseases that spread from animals to humans. Community transmission from human to human has largely contributed to increasing infection rates across the globe. When the novel coronavirus was first detected, it took just 69 days to infect 100000 patients, then increased to 200000 in 12 days, then 300000 in 4 days, and 400000 days in less than a day. As of 1 September 2021, there are well over two hundred and seventeen million cases worldwide. Of concern, at least four and a half million confirmed COVID-19 deaths have been recorded as of 1 September 2021. The World Health Organization (WHO) has advised that the COVID-19 pandemic is far from over.


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How to Cite

Suleman, M. H. (2021). A review analyzing what is COVID-19, its causes, pathogenesis, pathophysiology, and treatment. International Research Journal of Advanced Science, 2(2), 33-38. Retrieved from https://irjas.com/index.php/sciencejournal/article/view/48